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Dr Michael Mosley is a wonderful programme maker who is responsible for several other great documentaries I’ve mentioned before, including Medical Mavericks, The Story of Science, Frontline Medicine and several episodes of Horizon. Now he’s presenting a new three-part series called Pain, Pus & Poison: The Search for Modern Medicines.

The first episode deals with the search for medicines to relieve pain. Several of the stories he presents have been presented in his previous programmes, however it’s always nice to have an update. He tells the story of the development of ether for use in operations, which was marked by conflict between William T. G. Morton, who performed a painless tooth extraction with the drug in 1846, and Henry Jacob Bigelow, who arranged a demonstrations where ether was used in an operation on a patient’s neck tumor.

"Ether Day 1846" by Warren and Lucia Prosperi (2001)

“Ether Day 1846” by Warren and Lucia Prosperi (2001)

He also explains how the drugs Heroin and Aspirin were developed simultaneously and initially Heroin was selected as the preferred drug and marketed successfully by Bayer AG. Aspirin slowly grew in popularity as Heroin’s addictive properties began to cause concern and Aspirin became one of the most popular drugs in the world.

BayerHeroin

Mosley tests the medicines he is talking about on himself, which really brings his programmes to life, proving he’s really serious about what he’s talking about, or at least eager to get high! In this first episode, he conducts several staggering experiments, including rubbing cocaine into his eye before poking it and having himself intravenously drugged with sodium thiopental, to test its ability as a truth serum.

The show is incredibly engaging, and I particularly enjoy his explanations of how the painkillers actually function in the body, something I always wonder about when taking them! The episode concludes with a celebration of morphine, the drug that has endured for 200 years despite huge developments in medicine.

Episode 1: Pain is on iPlayer now, as is the next episode, Pus.

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